Opioid and Naloxone Alerts

Opioid and Naloxone Alerts

Key findings

  • 110 samples were checked: 66% were substances1 and 34% were used paraphernalia2
  • 71% of the samples checked were expected3 to be fentanyl, cocaine, or methamphetamine
  • 8% of the expected3 fentanyl samples checked were known to be associated with an overdose: all samples contained fentanyl and a benzodiazepine-related drug
  • 56% of the expected3 fentanyl samples checked contained at least one benzodiazepine-related drug
  • Etodesnitazene – an opioid with similar potency to fentanyl – presented for the first time in expected3 fentanyl samples checked

Expected fentanyl substances

  • 75% (15) of expected3 fentanyl substances checked4 contained fentanyl and other drugs, including:
  • 80% (12) contained caffeine
  • 53% (8) contained despropionyl fentanyl (4-ANPP) (!)
  • 53% (8) contained etizolam (benzodiazepine-related) (!)
  • 13% (2) contained etodesnitazene (!)
  • 7% (1) contained acetyl fentanyl (!)
  • o   7% (1) contained furanyl UF-17 (opioid-related) (!)

Unexpected noteworthy drugs found in other expected substances

  • 4% (2) of the remaining substances checked,4 meaning substances that weren’t expected3 to be fentanyl, contained an unexpected noteworthy drug, including:
  • 14% (2) of expected cocaine substances contained phenacetin (!)

Information from Wellington Dufferin Guelph Public Health suggests that “Red Fentanyl” could be involved in a number of recent overdoses. It’s important to assume that all substances circulating can be of higher toxicity.

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